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Mount Sinai Hospital


Brown, Theodore J. PhD: (Associate Professor, Department of Obstetrics & Gynaecology and the Department of Zoology; Cross appointment to the Department of Medicine, Division of Endocrinology and Metabolism MSH). Dr. Brown research includes studies of gonadal steroid mechanisms in growth regulation of cancer and in the hypothalamic regulation of reproductive function

Telephone: 416-586-4800 x 2996 416-586-4800 x 2451
E-mail: brown@mshri.on.ca                                                                                                                  

Daniel Drucker, MD (Active Staff, Clinician Scientist job description [95% protected research time]).  Research Interests: Dr. Drucker studies the synthesis, secretion and biological actions of proglucagon-derived peptides, including glucagon, GLP-1 and GLP-2.

Telephone: 416-361-2661Fax: 416-361-2669
Email: d.drucker@utoronto.ca
www.glucagon.com  www.mythyroid.com

I.G. Fantus, MD (Active Staff, Clinician Scientist job description [70% protected research time]). Major administrative responsibilities: Associate Dean of Research, University of Toronto, Director, Core Laboratory, Banting and Best Diabetes Center. Major research Interests: Investigation of the mechanism of insulin action with a focus on elucidating the pathophysiology of insulin resistance. Specifically, Dr. Fantus is studying cellular and molecular mechanisms of high glucose and free fatty acid-induced insulin resistance in adipose and muscle tissue. Secondly, Dr. Fantus has an interest in investigating the pathogenesis of chronic complications of Diabetes, particularly the ability of hyperglycemia to alter cell signaling                                                                                            

Telephone: 416-586-8665                                                                                                 
Fax: 416-361-2657                                                                                                               
il: fantus@mshri.on.ca

Denice Feig, MD
(Active Staff, Clinician Teacher job description [25% time protected for research]). Major administrative responsibilities: Head of the UHN/MSH Endocrinology of Pregnancy clinic and co-ordinator of the Masters course in Clinical Epidemiology called 'Evidence-based guidelines’. Dr. Feig teaches students and residents in three disciplines: endocrinology, internal medicine and obstetrics in the area of diabetes and other endocrine disorders in pregnancy. She also does clinical research in the area of Diabetes in Pregnancy and the effect of hyper and hypothyroidism in pregnancy on infants and newborns. She teaches seminars in Clinical Epidemiology and is involved in the development of evidence-based guidelines for preventive health.                                                                                      

Telephone: 416-586-8590                                                                                                  
Fax: 416-361-2657                                                                                                               
E-mail: dfeig@mtsinai.on.ca

Anthony Hanley, PhD (Staff Scientist with primary appointment to the Department of Nutritional Sciences, U of T and cross appointment to the UHN/MSH Division of Endocrinology and Metabolism. Dr. Hanley’s major areas of research interest include the metabolic and nutritional epidemiology of Type 2 diabetes mellitus associated complications, particularly among Aboriginal Canadians and other high risk groups. In addition, he has an interest in the validation and application of surrogate measures of insulin resistance and beta cell function.

Telephone: 416-978-3616
Fax: 416-978-5882

Jacqueline James, MD
(Active Staff, Clinician Educator job description). Major administrative responsibilities: Director of the Wightman Berris Academy and Course Director for the undergraduate course ‘The Art and Science of Clinical Medicine II’, a major undergraduate course for all second year medical students across the University of Toronto. Dr. James is also the Chair of the Banting and Best Diabetes Center Care and Education Committee. Her major activities include patient care, medical education and administration.                                             

Telephone: 416-586-8369
Fax: 416-361-2662

Stephen J. Lye, MD, PhD:
(Professor, Department of Obstetrics and Gynaecology; Senior Investigator, Samuel Lunenfeld Research Institute; Cross appointment to the Department of Medicine, Division of Endocrinology and Metabolism, MSH). Research interest in endocrinology of pregnancy; molecular regulation of myometrial, placental/fetal development, onset of term/pre-term labour and prevention of preterm delivery.                                           

Telephone: 416-586-4800 x 8460
Fax: 416-586-8857
Email: lye@mshri.on.ca

Stephen Matthews, PhD (Professor, Department of Physiology and Cross appointments to the Department of Obstetrics and Gynaecology and Department of Medicine, Division of Endocrinology and Metabolism. Dr. Matthews research focuses on the regulation and plasticity of neuroendocrine systems during development.                                                          

Telephone: 416-978-1974
Fax: 416-978-4940
Email: stephen.matthews@utoronto.ca

Adam Millar, MD (Clinical Associate, Division of Endocrinology, Department of Medicine, University of Toronto)Dr. Millar is a general endocrinologist whose main area of clinical interest is andrology. His andrology clinics are located at the Murray Koffler Urologic Wellness Centre at Mount Sinai Hospital, and focus on the investigation and management of male-related health conditions such as hypogonadism, infertilty and sexual dysfunction. He is completing a Master of Science Degree in Community Health with a special focus on Health Practitioner Teacher Education. His educational interests include teaching of endocrinology and andrology-related subject matter to undergraduate and postgraduate medical trainees.

Tel 416 586-4800 x3939
Fax 416 619-5523

Bruce Perkins, MD
(Clinician Investigator, Division of Endocrinology, Department of Medicine, University of Toronto).
Dr. Perkins' research initiatives focus on using epidemiological techniques to explore the natural history of diabetes complications and novel strategies fro their prevention.   His major clinical reserch areas include: 1. Exploring the pattern of renal function decline adn its determinants early in teh course of nephropathy in type 1 diabetes.  2. Characterizzing teh natural history of diabetic polyneuropathy and definin the best methods for clnical assessment. 3. Diabetes technologies, including the process of care for intensive insulin therapy.

Telephone: 416.586.8763
Fax: 647.826.1528
Email:  bperkins@mtsinai.on.ca

Ravi Retnakaran, MD, MSc, FRCP(C) (Active Staff, Clinician Scientist)Major research interest: Dr. Retnakaran's research program focuses on the early pathophysiology of type 2 diabetes (T2DM) and cardiovascular disease (CVD) as studied through long-term longitudinal cardio-metabolic characterization of subjects at varying degrees of risk for the future development of these disorders. He also has interests in the evaluation of beta-cell function in clinical studies and the effects of insulin therapy on beta-cell function.

Telephone: 416-586-4800 Ext. 3941
Fax: 416-586-8853
Email: rretnakaran@mtsinai.on.ca

Paul Walfish, MD
(Emeritus Professor). Dr. Walfish runs a very busy clinic specializing in the treatment of thyroid disorders and endocrine malignancy. His research into the regulation of thyroid hormone action by nuclear receptor co-activators is funded by the Canadian Institutes of Health Research.

Telephone: 416-586-4437
Fax: 416-586-8861
E-mail: walfish@mshri.on.ca

B. Zinman, MD
(Active Staff, Clinician Scientist job description [70% protected research time]). Major administrative responsibilities: Director, Leadership Sinai Centre for Diabetes. Major Research Interests: Dr. Zinman has contributed significantly to the understanding of the relationship between metabolic control and the long-term complications of Diabetes. Dr. Zinman has been a principal investigator in a number of landmark clinical studies that have changed the practice of diabetes care. More recently his work with aboriginal people has highlighted the devastating impact of diabetes on Canadian First Nation populations.

Telephone: 416-586-8747
Fax: 416-586-4740
E-mail: zinman@lunenfeld.ca


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